Generation of iPS cells using defined factors linked via the self-cleaving 2A sequences in a single open reading frame

Generation of induced pluripotent stem (iPS) cells from somatic cells has been achieved successfully by simultaneous viral transduction of defined reprogramming transcription factors (TFs). However, the process requires multiple viral vectors for gene delivery. As a result, generated iPS cells harbo...

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Main Authors: Shao, Lijian, Feng, Wei, Sun, Yan, Bai, Hao, Liu, Jun, Currie, Caroline, Kim, Jaejung, Gama, Rafael, Wang, Zack, Qian, Zhijian, Liaw, Lucy, Wu, Wen-Shu
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2009
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2821711/
https://ncbi.nlm.nih.gov/pubmed/19238173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2009.20
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