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Toll-like receptor 2 on inflammatory monocytes induces type I interferon in response to viral but not bacterial ligands

Despite the paradigm that the innate immune system uses nucleic acid-specific receptors to detect viruses due to a lack of other conserved features, a number of viruses are recognized by TLR2 and TLR4. The relevance of this recognition for antiviral immunity remains largely unexplained. Here we repo...

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Detalhes bibliográficos
Main Authors: Barbalat, Roman, Lau, Laura, Locksley, Richard M., Barton, Gregory M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2821672/
https://ncbi.nlm.nih.gov/pubmed/19801985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.1792
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