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What single-channel analysis tells us of the activation mechanism of ligand-gated channels: the case of the glycine receptor

Glycine receptors are, in several ways, the member of the nicotinic superfamily that is best-suited for single-channel recording. That means that they are ideal for testing ideas about how activation proceeds in a ligand-gated ion channel from the binding of the agonist to the opening of the channel...

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Autore principale: Sivilotti, Lucia G
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2821546/
https://ncbi.nlm.nih.gov/pubmed/19770192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2009.178525
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