Membrane attachment activates dnaA protein, the initiation protein of chromosome replication in Escherichia coli.
ADP and ATP are tightly bound to dnaA protein and are crucial to its function in DNA replication; the exchange of these nucleotides is effected specifically by the acidic phospholipids (cardiolipin and phosphatidylglycerol) present in Escherichia coli membranes [Sekimizu, K. & Kornberg, A. (1988) J....
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
1988
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC282152/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2845401/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.19.7202 |
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