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Membrane attachment activates dnaA protein, the initiation protein of chromosome replication in Escherichia coli.

ADP and ATP are tightly bound to dnaA protein and are crucial to its function in DNA replication; the exchange of these nucleotides is effected specifically by the acidic phospholipids (cardiolipin and phosphatidylglycerol) present in Escherichia coli membranes [Sekimizu, K. & Kornberg, A. (1988) J....

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Yung, B Y, Kornberg, A
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1988
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC282152/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2845401/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.19.7202
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