Photoaffinity labeling of the multidrug-resistance-related P-glycoprotein with photoactive analogs of verapamil.
Verapamil, a phenylalkylamine calcium channel blocker, has been shown to reverse multidrug resistance in tumor cells, possibly by increasing drug retention through interaction with an outward drug transporter of the resistant cells. In this study two photoactive radioactive analogs of verapamil, N-(...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Hovedforfatter: | |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1988
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC282149/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2902625/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.19.7187 |
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