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Regulation of CCR5 Expression in Human Placenta: Insights from a Study of Mother-to-Child Transmission of HIV in Malawi

BACKGROUND: Human promoter polymorphisms in the chemokine co-receptor 5 gene (CCR5) have been noted for association with mother-to-child transmission of HIV (HIV MTCT) as well as reduced receptor expression in vitro, but have not been clearly associated with CCR5 expression in vivo. Placental expres...

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Detalhes bibliográficos
Main Authors: Joubert, Bonnie R., Franceschini, Nora, Mwapasa, Victor, North, Kari E., Meshnick, Steven R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2821402/
https://ncbi.nlm.nih.gov/pubmed/20169157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009212
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