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MATERNAL-FETAL DNA ADMIXTURE IS ASSOCIATED WITH INTRAPARTUM HIV-1 MOTHER-TO-CHILD TRANSMISSION IN BLANTYRE, MALAWI

BACKGROUND: The mechanism of HIV-1 mother-to-child transmission (MTCT) is not well described. METHODS: Of 328 HIV-infected mother-infant pairs, we identified discordant ACE and GSTM1 alleles in 91. Maternal alleles in cord blood were quantified with real-time PCR as indicators of microtransfusions....

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Detalhes bibliográficos
Main Authors: Kwiek, Jesse J., Arney, Leslie A., Harawa, Visopo, Petersen, Bonnie, Mwapasa, Victor, Rogerson, Stephen J., Meshnick, Steven R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2443405/
https://ncbi.nlm.nih.gov/pubmed/18444794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/587646
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