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Circular permutation of ligand-binding module improves dynamic range of genetically encoded FRET-based nanosensor

Quantitative measurement of small molecules with high spatiotemporal resolution provides a solid basis for correct understanding and accurate modeling of metabolic regulation. A promising approach toward this goal is the FLIP (fluorescent indicator protein) nanosensor based on bacterial periplasmic...

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Detalhes bibliográficos
Main Authors: Okada, Satoshi, Ota, Kazuhisa, Ito, Takashi
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2821270/
https://ncbi.nlm.nih.gov/pubmed/19827096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.266
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