Efficient computation of parameter sensitivities of discrete stochastic chemical reaction networks

Parametric sensitivity of biochemical networks is an indispensable tool for studying system robustness properties, estimating network parameters, and identifying targets for drug therapy. For discrete stochastic representations of biochemical networks where Monte Carlo methods are commonly used, sen...

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Bibliografiska uppgifter
Huvudupphovsmän: Rathinam, Muruhan, Sheppard, Patrick W., Khammash, Mustafa
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Institute of Physics 2010
Ämnen:
Theoretical Methods and Algorithms
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2821153/
https://ncbi.nlm.nih.gov/pubmed/20095724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.3280166
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