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Efficient computation of parameter sensitivities of discrete stochastic chemical reaction networks
Parametric sensitivity of biochemical networks is an indispensable tool for studying system robustness properties, estimating network parameters, and identifying targets for drug therapy. For discrete stochastic representations of biochemical networks where Monte Carlo methods are commonly used, sen...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Institute of Physics
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2821153/ https://ncbi.nlm.nih.gov/pubmed/20095724 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.3280166 |
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