Evidence of Early B-Cell Dysregulation in Simian Immunodeficiency Virus Infection: Rapid Depletion of Naïve and Memory B-Cell Subsets with Delayed Reconstitution of the Naïve B-Cell Population

Despite eliciting a robust antibody response in humans, several studies in human immunodeficiency virus (HIV)-infected patients have demonstrated the presence of B-cell deficiencies during the chronic stage of infection. While several explanations for the HIV-induced B-cell deficit have been propose...

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Hlavní autoři: Kuhrt, David, Faith, Seth A., Leone, Amanda, Rohankedkar, Mukta, Sodora, Donald L., Picker, Louis J., Cole, Kelly Stefano
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2010
Témata:
Pathogenesis and Immunity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820932/
https://ncbi.nlm.nih.gov/pubmed/20032183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01966-09
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