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HIV-1 Nef Inhibits Ruffles, Induces Filopodia, and Modulates Migration of Infected Lymphocytes

The HIV-1 Nef protein is a pathogenic factor modulating the behavior of infected cells. Nef induces actin cytoskeleton changes and impairs cell migration toward chemokines. We further characterized the morphology, cytoskeleton dynamics, and motility of HIV-1-infected lymphocytes. By using scanning e...

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Autors principals: Nobile, Cinzia, Rudnicka, Dominika, Hasan, Milena, Aulner, Nathalie, Porrot, Françoise, Machu, Christophe, Renaud, Olivier, Prévost, Marie-Christine, Hivroz, Claire, Schwartz, Olivier, Sol-Foulon, Nathalie
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820911/
https://ncbi.nlm.nih.gov/pubmed/20015995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02230-09
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