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The Latent Origin of Replication of Epstein-Barr Virus Directs Viral Genomes to Active Regions of the Nucleus

The Epstein-Barr virus efficiently infects human B cells. The EBV genome is maintained extrachromosomally and replicates synchronously with the host's chromosomes. The latent origin of replication (oriP) guarantees plasmid stability by mediating two basic functions: replication and segregation...

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Detalles Bibliográficos
Main Authors: Deutsch, Manuel J., Ott, Elisabeth, Papior, Peer, Schepers, Aloys
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820910/
https://ncbi.nlm.nih.gov/pubmed/20032186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01909-09
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