The Affinity of EBNA1 for Its Origin of DNA Synthesis Is a Determinant of the Origin's Replicative Efficiency

Epstein-Barr virus (EBV) replicates its genome as a licensed plasmid in latently infected cells. Although replication of this plasmid is essential for EBV latent infection, its synthesis still fails for 16% of the templates in S phase. In order to understand these failures, we sought to determine wh...

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Bibliographische Detailangaben
Hauptverfasser: Lindner, Scott E., Zeller, Krisztina, Schepers, Aloys, Sugden, Bill
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2008
Schlagworte:
Genome Replication and Regulation of Viral Gene Expression
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2395165/
https://ncbi.nlm.nih.gov/pubmed/18385243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00332-08
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