Structural Basis for Cooperative Binding of EBNA1 to the Epstein-Barr Virus Dyad Symmetry Minimal Origin of Replication

Epstein-Barr virus is associated with several human malignancies, including nasopharyngeal carcinoma, gastric cancer, and lymphoma. Latently infected cells carry a circularized EBV episome where the origin of replication (oriP) is comprised of two elements: the family of repeats (FR) and dyad symmet...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Malecka, Kimberly A., Dheekollu, Jayaraju, Deakyne, Julianna S., Wiedmer, Andreas, Ramirez, Ursula D., Lieberman, Paul M., Messick, Troy E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6675896/
https://ncbi.nlm.nih.gov/pubmed/31142669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00487-19
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