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Conserved Motifs within Ebola and Marburg Virus VP40 Proteins Are Important for Stability, Localization, and Subsequent Budding of Virus-Like Particles

The filovirus VP40 protein is capable of budding from mammalian cells in the form of virus-like particles (VLPs) that are morphologically indistinguishable from infectious virions. Ebola virus VP40 (eVP40) contains well-characterized overlapping L domains, which play a key role in mediating efficien...

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Autors principals: Liu, Yuliang, Cocka, Luis, Okumura, Atsushi, Zhang, Yong-An, Sunyer, J. Oriol, Harty, Ronald N.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820906/
https://ncbi.nlm.nih.gov/pubmed/20032189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02034-09
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