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Dystrophin Glycoprotein Complex-associated Gβγ Subunits Activate Phosphatidyl Inositol-3-Kinase/Akt signaling in Skeletal Muscle in a Laminin-dependent Manner

Previously, we showed that laminin-binding to the dystrophin glycoprotein complex (DGC) of skeletal muscle causes a heterotrimeric G-protein, (Gαβγ) to bind, changing the activation state of the Gsα subunit. Others have shown that laminin-binding to the DGC also leads to Akt activation. Gβγ, release...

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Détails bibliographiques
Auteurs principaux: Xiong, Yongmin, Zhou, Yanwen, Jarrett, Harry W.
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820875/
https://ncbi.nlm.nih.gov/pubmed/19117013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.21684
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