Generation of lymphokine-activated killer cells: synergy between tumor necrosis factor and interleukin 2.

Large granular lymphocytes (LGL) can be activated by interleukin 2 (IL-2) to lymphokine-activated killers (LAK). The effect of tumor necrosis factor (TNF) on LAK generation was investigated. TNF was found to act synergistically with low concentrations of IL-2 (0.10-0.25 ng/ml), which were ineffectiv...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Chouaib, S, Bertoglio, J, Blay, J Y, Marchiol-Fournigault, C, Fradelizi, D
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1988
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC282081/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3045826/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.18.6875
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