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Generation of lymphokine-activated killer cells: synergy between tumor necrosis factor and interleukin 2.

Large granular lymphocytes (LGL) can be activated by interleukin 2 (IL-2) to lymphokine-activated killers (LAK). The effect of tumor necrosis factor (TNF) on LAK generation was investigated. TNF was found to act synergistically with low concentrations of IL-2 (0.10-0.25 ng/ml), which were ineffectiv...

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Publicado no:Proc Natl Acad Sci U S A
Principais autores: Chouaib, S, Bertoglio, J, Blay, J Y, Marchiol-Fournigault, C, Fradelizi, D
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1988
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC282081/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3045826/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.18.6875
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