Huntingtin-associated Protein-1 Interacts with Pro-brain-derived Neurotrophic Factor and Mediates Its Transport and Release

Brain-derived neurotrophic factor (BDNF) plays a pivotal role in brain development and synaptic plasticity. It is synthesized as a precursor (pro-BDNF), sorted into the secretory pathway, transported along dendrites and axons, and released in an activity-dependent manner. Mutant Huntingtin with expa...

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Bibliografiske detaljer
Main Authors: Wu, Linda Lin-yan, Fan, Yongjun, Li, Shihua, Li, Xiao-Jiang, Zhou, Xin-Fu
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2010
Fag:
Neurobiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820788/
https://ncbi.nlm.nih.gov/pubmed/19996106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.073197
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