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Applicability of the Triad Concept for the Positional Specificity of Mammalian Lipoxygenases
The nomenclature of lipoxygenases (LOXs) is partly based on the positional specificity of arachidonic acid oxygenation, but there is no unifying concept explaining the mechanistic basis of this enzyme property. According to the triad model, Phe-353, Ile-418, and Ile-593 of the rabbit 12/15-LOX form...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2820765/ https://ncbi.nlm.nih.gov/pubmed/20026599 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.057802 |
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