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Human GTSE-1 Regulates p21(CIP1/WAF1) Stability Conferring Resistance to Paclitaxel Treatment

p21(CIP1/WAF1) belongs to the CIP/KIP family of Cdk inhibitors, and its expression is tightly controlled during the cell cycle, mainly by transcriptional and post-translational mechanisms. Fine regulation of p21(CIP1/WAF1) levels is critical for cell cycle control and for cellular response to stress...

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Detalhes bibliográficos
Main Authors: Bublik, Débora Rosa, Scolz, Massimiliano, Triolo, Gianluca, Monte, Martín, Schneider, Claudio
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820756/
https://ncbi.nlm.nih.gov/pubmed/20018861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.045948
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