The EGF/CSF-1 Paracrine Invasion Loop can be Triggered by Heregulin Beta 1 and CXCL12

An important step in the process of metastasis from the primary tumor is invasive spread into the surrounding stroma. Using an in vivo invasion assay, we have previously shown that imposed gradients of EGF or CSF-1 can induce invasion through an EGF/CSF-1 paracrine loop between cancer cells and macr...

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Hauptverfasser: Hernandez, Lorena, Smirnova, Tatiana, Kedrin, Dmitriy, Wyckoff, Jeffrey, Zhu, Liyin, Stanley, E. Richard., Cox, Dianne, Muller, William J., Pollard, Jeffrey W., Van Rooijen, Nico, Segall, Jeffrey E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820720/
https://ncbi.nlm.nih.gov/pubmed/19293185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-2871
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