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The EGF/CSF-1 Paracrine Invasion Loop can be Triggered by Heregulin Beta 1 and CXCL12

An important step in the process of metastasis from the primary tumor is invasive spread into the surrounding stroma. Using an in vivo invasion assay, we have previously shown that imposed gradients of EGF or CSF-1 can induce invasion through an EGF/CSF-1 paracrine loop between cancer cells and macr...

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Detalhes bibliográficos
Main Authors: Hernandez, Lorena, Smirnova, Tatiana, Kedrin, Dmitriy, Wyckoff, Jeffrey, Zhu, Liyin, Stanley, E. Richard., Cox, Dianne, Muller, William J., Pollard, Jeffrey W., Van Rooijen, Nico, Segall, Jeffrey E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820720/
https://ncbi.nlm.nih.gov/pubmed/19293185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-2871
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