Discovery of molecular subtypes in leiomyosarcoma through integrative molecular profiling

Leiomyosarcoma (LMS) is a soft tissue tumor with a significant degree of morphologic and molecular heterogeneity. We employed integrative molecular profiling to discover and characterize molecular subtypes of LMS. Gene expression profiling was performed on 51 LMS samples. Unsupervised clustering dem...

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Hauptverfasser: Beck, Andrew H, Lee, Cheng-Han, Witten, Daniela M, Gleason, Briana C, Edris, Badreddin, Espinosa, Inigo, Zhu, Shirley, Li, Rui, Montgomery, Kelli D, Marinelli, Robert J, Tibshirani, Robert, Hastie, Trevor, Jablons, David M, Rubin, Brian P, Fletcher, Christopher D, West, Robert B, van de Rijn, Matt
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820592/
https://ncbi.nlm.nih.gov/pubmed/19901961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2009.381
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