Discovery of molecular subtypes in leiomyosarcoma through integrative molecular profiling

Leiomyosarcoma (LMS) is a soft tissue tumor with a significant degree of morphologic and molecular heterogeneity. We employed integrative molecular profiling to discover and characterize molecular subtypes of LMS. Gene expression profiling was performed on 51 LMS samples. Unsupervised clustering dem...

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Bibliographic Details
Main Authors: Beck, Andrew H, Lee, Cheng-Han, Witten, Daniela M, Gleason, Briana C, Edris, Badreddin, Espinosa, Inigo, Zhu, Shirley, Li, Rui, Montgomery, Kelli D, Marinelli, Robert J, Tibshirani, Robert, Hastie, Trevor, Jablons, David M, Rubin, Brian P, Fletcher, Christopher D, West, Robert B, van de Rijn, Matt
Format: Artigo
Language:Inglês
Published: 2009
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820592/
https://ncbi.nlm.nih.gov/pubmed/19901961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2009.381
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