In vitro and in vivo Functional Characterization of Gutless Recombinant SV40-derived CFTR Vectors

In cystic fibrosis (CF) respiratory failure caused by progressive airway obstruction and tissue damage is primarily a result of the aberrant inflammatory responses to lung infections with Pseudomonas aeruginosa. Despite considerable improvement in patient survival, conventional therapies are mainly...

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Detalhes bibliográficos
Main Authors: Mueller, Christian, Strayer, Marlene S, Sirninger, Jeffery, Braag, Sofia, Branco, Francisco, Louboutin, Jean-Pierre, Flotte, Terence R., Strayer, David S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820588/
https://ncbi.nlm.nih.gov/pubmed/19890354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2009.137
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