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In vivo gene transfer into rat bone marrow progenitor cells using rSV40 viral vectors
Hematopoietic stem cell (HSC) gene transfer has been attempted almost entirely ex vivo and has been limited by cytokine-induced loss of self-renewal capacity and transplantation-related defects in homing and engraftment. Here, we attempted to circumvent such limitations by injecting vectors directly...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The American Society of Hematology
2005
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1895314/ https://ncbi.nlm.nih.gov/pubmed/15994284 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-01-0028 |
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