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A Kinetic Model of Dopamine- and Calcium-Dependent Striatal Synaptic Plasticity
Corticostriatal synapse plasticity of medium spiny neurons is regulated by glutamate input from the cortex and dopamine input from the substantia nigra. While cortical stimulation alone results in long-term depression (LTD), the combination with dopamine switches LTD to long-term potentiation (LTP),...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Public Library of Science
2010
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2820521/ https://ncbi.nlm.nih.gov/pubmed/20169176 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000670 |
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