Variable viral clearance despite adequate ganciclovir plasma levels during valganciclovir treatment for cytomegalovirus disease in D+/R- transplant recipients

BACKGROUND: Valganciclovir, the oral prodrug of ganciclovir, has been demonstrated equivalent to iv ganciclovir for CMV disease treatment in solid organ transplant recipients. Variability in ganciclovir exposure achieved with valganciclovir could be implicated as a contributing factor for explaining...

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Detalhes bibliográficos
Main Authors: Perrottet, Nancy, Manuel, Oriol, Lamoth, Frédéric, Venetz, Jean-Pierre, Sahli, Roland, Decosterd, Laurent A, Buclin, Thierry, Pascual, Manuel, Meylan, Pascal
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820479/
https://ncbi.nlm.nih.gov/pubmed/20053269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2334-10-2
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