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Genomic sequencing and in vivo footprinting of an expression-specific DNase I-hypersensitive site of avian vitellogenin II promoter reveal a demethylation of a mCpG and a change in specific interactions of proteins with DNA.

Genomic sequencing was used to study the in vivo methylation pattern of two CpG sites in the promoter region of the avian vitellogenin gene. The CpG at position +10 was fully methylated in DNA isolated from tissues that do not express the gene but was unmethylated in the liver of mature hens and est...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Saluz, H P, Feavers, I M, Jiricny, J, Jost, J P
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1988
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC282044/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3413118/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.18.6697
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