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Activation of factor VII bound to tissue factor: a key early step in the tissue factor pathway of blood coagulation.

Whether the factor VII/tissue factor complex that forms in tissue factor-dependent blood coagulation must be activated to factor VIIa/tissue factor before it can activate its substrates, factor X and factor IX, has been a difficult question to answer because the substrates, once activated, back-acti...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Rao, L V, Rapaport, S I
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1988
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC282042/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3261869/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.18.6687
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