Bacterial nitric oxide detoxification prevents host cell S-nitrosothiol formation: a novel mechanism of bacterial pathogenesis

S-nitrosylation is an important mediator of multiple nitric oxide-dependent biological processes, including eukaryotic cellular events such as macrophage apoptosis and proinflammatory signaling. Many pathogenic bacteria possess NO detoxification mechanisms, such as the nitric oxide reductase (NorB)...

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Autors principals: Laver, Jay R., Stevanin, Tânia M., Messenger, Sarah L., Lunn, Amy Dehn, Lee, Margaret E., Moir, James W. B., Poole, Robert K., Read, Robert C.
Format: Artigo
Idioma:Inglês
Publicat: The Federation of American Societies for Experimental Biology 2010
Matèries:
Research Communications
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820398/
https://ncbi.nlm.nih.gov/pubmed/19720623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.08-128330
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