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A direct protein-protein interaction is involved in the suppression of β-catenin transcription by retinoid X receptor α in colorectal cancer cells

Using both mammalian two-hybrid assay in vivo and immuno-precipitation in vitro we found that retinoid X receptor α (RXRα) directly interacted with β-catenin and suppressed β-catenin transcriptional activity and protein expression in colorectal cancer cells. But, reduction of RXRα by small interferi...

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Main Authors: Han, Anjia, Tong, Chang, Hu, Dong, Bi, Xiuli, Yang, Wancai
格式: Artigo
語言:Inglês
出版: 2007
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820390/
https://ncbi.nlm.nih.gov/pubmed/18196974
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