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A direct protein-protein interaction is involved in the suppression of β-catenin transcription by retinoid X receptor α in colorectal cancer cells
Using both mammalian two-hybrid assay in vivo and immuno-precipitation in vitro we found that retinoid X receptor α (RXRα) directly interacted with β-catenin and suppressed β-catenin transcriptional activity and protein expression in colorectal cancer cells. But, reduction of RXRα by small interferi...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2820390/ https://ncbi.nlm.nih.gov/pubmed/18196974 |
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