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Gating mechanism of the Influenza A M2 channel revealed by 1 and 2D-IR spectroscopies
The pH-controlled M2 protein from Influenza is a critical component of the virus, serving as a target for aminoadamantane anti-flu agents that block its H(+) channel activity. To better understand its H(+)-gating mechanism, we investigated M2 in lipid bilayers with a new combination of IR spectrosco...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2820372/ https://ncbi.nlm.nih.gov/pubmed/19217395 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2008.12.015 |
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