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Quantitative analysis of Akt phosphorylation and activity in response to EGF and insulin treatment

The protein kinase Akt is a critical regulator of cell function and its overexpression and activation have been functionally linked to numerous pathologies such as cancer. Previous reports regarding the mechanism regulating Akt's activation have revealed two phosphorylation events, at threonine...

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Hlavní autoři: Kumar, Neil, Afeyan, Raffi, Sheppard, Sarah, Harms, Brian, Lauffenburger, Douglas A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820294/
https://ncbi.nlm.nih.gov/pubmed/17214972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2006.12.188
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