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Quantitative analysis of Akt phosphorylation and activity in response to EGF and insulin treatment

The protein kinase Akt is a critical regulator of cell function and its overexpression and activation have been functionally linked to numerous pathologies such as cancer. Previous reports regarding the mechanism regulating Akt's activation have revealed two phosphorylation events, at threonine...

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Detalhes bibliográficos
Main Authors: Kumar, Neil, Afeyan, Raffi, Sheppard, Sarah, Harms, Brian, Lauffenburger, Douglas A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820294/
https://ncbi.nlm.nih.gov/pubmed/17214972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2006.12.188
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