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Functional Analysis of the Interplay between Translation Termination, Selenocysteine Codon Context, and Selenocysteine Insertion Sequence-binding Protein 2

A selenocysteine insertion sequence (SECIS) element in the 3′-untranslated region and an in-frame UGA codon are the requisite cis-acting elements for the incorporation of selenocysteine into selenoproteins. Equally important are the trans-acting factors SBP2, Sec-tRNA([Ser]Sec), and eEFSec. Multiple...

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Detalhes bibliográficos
Main Authors: Gupta, Malavika, Copeland, Paul R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820277/
https://ncbi.nlm.nih.gov/pubmed/17954931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M707061200
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