Genome-wide Association Study in a High-Risk Isolate for Multiple Sclerosis Reveals Associated Variants in STAT3 Gene

Genetic risk for multiple sclerosis (MS) is thought to involve both common and rare risk alleles. Recent GWAS and subsequent meta-analysis have established the critical role of the HLA locus and identified new common variants associated to MS. These variants have small odds ratios (ORs) and explain...

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Bibliografiske detaljer
Main Authors: Jakkula, Eveliina, Leppä, Virpi, Sulonen, Anna-Maija, Varilo, Teppo, Kallio, Suvi, Kemppinen, Anu, Purcell, Shaun, Koivisto, Keijo, Tienari, Pentti, Sumelahti, Marja-Liisa, Elovaara, Irina, Pirttilä, Tuula, Reunanen, Mauri, Aromaa, Arpo, Oturai, Annette Bang, Søndergaard, Helle Bach, Harbo, Hanne F., Mero, Inger-Lise, Gabriel, Stacey B., Mirel, Daniel B., Hauser, Stephen L., Kappos, Ludwig, Polman, Chris, De Jager, Philip L., Hafler, David A., Daly, Mark J., Palotie, Aarno, Saarela, Janna, Peltonen, Leena
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2010
Fag:
Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820168/
https://ncbi.nlm.nih.gov/pubmed/20159113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2010.01.017
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