No evidence for shared etiology in two demyelinative disorders, MS and PLOSL

Loss-of-function mutations of DAP12 and TREM2 cause a recessively inherited disease PLOSL, manifesting in brain white matter. The genes of the DAP12-TREM2 signaling receptor are located on 19q13.12 and 6p21.1, to which linkage has been observed also in families affected by another immune-mediated de...

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Detalhes bibliográficos
Main Authors: Sulonen, Anna-Maija, Kallio, Suvi P., Ellonen, Pekka, Suvela, Minna, Elovaara, Irina, Koivisto, Keijo, Pirttilä, Tuula, Reunanen, Mauri, Tienari, Pentti J., Palotie, Aarno, Peltonen, Leena, Saarela, Janna
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2682253/
https://ncbi.nlm.nih.gov/pubmed/19019460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2008.10.005
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