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Inactivation of neuronal forebrain A(2A) receptors protects dopaminergic neurons in a mouse model of Parkinson’s disease

Adenosine A(2A) receptors antagonists produce neuroprotective effects in animal models of Parkinson’s disease (PD). Since neuroinflammation is involved in PD pathogenesis, both neuronal and glial A(2A) receptors might participate to neuroprotection. We employed complementary pharmacologic and geneti...

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Hlavní autoři: Carta, Anna R, Kachroo, Anil, Schintu, Nicoletta, Xu, Kui, Schwarzschild, Michael A., Wardas, Jadwiga, Morelli, Micaela
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820161/
https://ncbi.nlm.nih.gov/pubmed/19817968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2009.06425.x
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