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Improving the treatment of non-Hodgkin lymphoma with antibody-targeted radionuclides
Radioimmunotherapy of non-Hodgkin lymphoma consists of a (90)Y- or (131)I-labeled murine anti-CD20 IgG, but both agents also include a substantial dose of unlabeled anti-CD20 IgG given immediately before the radioconjugate to reduce its uptake in the spleen (primary normal B-cell antigen sink); this...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2820147/ https://ncbi.nlm.nih.gov/pubmed/20127947 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.24802 |
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