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Improving the treatment of non-Hodgkin lymphoma with antibody-targeted radionuclides

Radioimmunotherapy of non-Hodgkin lymphoma consists of a (90)Y- or (131)I-labeled murine anti-CD20 IgG, but both agents also include a substantial dose of unlabeled anti-CD20 IgG given immediately before the radioconjugate to reduce its uptake in the spleen (primary normal B-cell antigen sink); this...

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Autors principals: Sharkey, Robert M, Karacay, Habibe, Goldenberg, David M.
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820147/
https://ncbi.nlm.nih.gov/pubmed/20127947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.24802
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