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The influence of proteasome inhibitor MG132, external radiation and unlabeled antibody on the tumor uptake and biodistribution of (188)Re-labeled anti-E6 C1P5 antibody in cervical cancer in mice

BACKGROUND: Human Papillomavirus (HPV) infection is considered a necessary step for the development of cervical cancer and >95% of all cervical cancers have detectable HPV sequences. We have recently demonstrated the efficacy of radioimmunotherapy (RIT) which targeted viral oncoprotein E6 in trea...

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Detalhes bibliográficos
Main Authors: Phaeton, Rébécca, Wang, Xing Guo, Einstein, Mark H., Goldberg, Gary L., Casadevall, Arturo, Dadachova, Ekaterina
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820134/
https://ncbi.nlm.nih.gov/pubmed/20127955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.24794
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