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Associations between polymorphisms in glucuronidation and sulfation enzymes and mammographic breast density in premenopausal women in the United States
OBJECTIVE: Sex hormones are metabolized to less active compounds via (i) glucuronidation, catalyzed by UDP-glucuronosyltransferases (UGT) and (ii) sulfation, catalyzed by sulfotransferases (SULT). Functional UGT and SULT polymorphisms can affect clearance of sex hormones, thereby influencing exposur...
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| Главные авторы: | , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2820123/ https://ncbi.nlm.nih.gov/pubmed/20142249 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-09-0898 |
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