Associations between polymorphisms in glucuronidation and sulfation enzymes and mammographic breast density in premenopausal women in the United States

OBJECTIVE: Sex hormones are metabolized to less active compounds via (i) glucuronidation, catalyzed by UDP-glucuronosyltransferases (UGT) and (ii) sulfation, catalyzed by sulfotransferases (SULT). Functional UGT and SULT polymorphisms can affect clearance of sex hormones, thereby influencing exposur...

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Main Authors: Yong, Mellissa, Schwartz, Stephen M., Atkinson, Charlotte, Makar, Karen W., Thomas, Sushma S., Newton, Katherine M., Aiello Bowles, Erin J., Holt, Victoria L., Leisenring, Wendy M., Lampe, Johanna W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820123/
https://ncbi.nlm.nih.gov/pubmed/20142249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-09-0898
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