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Activity-Dependent Anchoring of Importin α at the Synapse Involves Regulated Binding to the Cytoplasmic Tail of the NR1-1a Subunit of the NMDA Receptor

Synaptic plasticity, the capacity of neurons to change the strength of their connections with experience, provides a mechanism for learning and memory in the brain. Long-term plasticity requires new transcription, indicating that synaptically generated signals must be transported to the nucleus. Pre...

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Autori principali: Jeffrey, Rachel A., Ch'ng, Toh Hean, O'Dell, Thomas J., Martin, Kelsey C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2819930/
https://ncbi.nlm.nih.gov/pubmed/20016075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3314-09.2009
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