CB(1) cannabinoid receptors promote oxidative stress and cell death in murine models of doxorubicin-induced cardiomyopathy and in human cardiomyocytes

AIMS: Here we investigated the mechanisms by which cardiovascular CB(1) cannabinoid receptors may modulate the cardiac dysfunction, oxidative stress, and interrelated cell death pathways associated with acute/chronic cardiomyopathy induced by the widely used anti-tumour compound doxorubicin (DOX). M...

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Hauptverfasser: Mukhopadhyay, Partha, Rajesh, Mohanraj, Bátkai, Sándor, Patel, Vivek, Kashiwaya, Yoshihiro, Liaudet, Lucas, Evgenov, Oleg V., Mackie, Ken, Haskó, György, Pacher, Pál
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2010
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2819835/
https://ncbi.nlm.nih.gov/pubmed/19942623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvp369
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