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Inositol Hexaphosphate Suppresses Growth and Induces Apoptosis in Prostate Carcinoma Cells in Culture and Nude Mouse Xenograft: PI3K-Akt Pathway as Potential Target

Constitutive activation of phosphoinositide 3-kinase (PI3K)-Akt pathway transmits growth regulatory signals which play a central role in promoting survival, proliferation and angiogenesis in human prostate cancer (PCa) cell. Here we assessed inositol hexaphosphate (IP6) efficacy against invasive hum...

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Detalhes bibliográficos
Main Authors: Gu, Mallikarjuna, Roy, Srirupa, Raina, Komal, Agarwal, Chapla, Agarwal, Rajesh
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2819750/
https://ncbi.nlm.nih.gov/pubmed/19920184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-2805
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