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Inositol Hexaphosphate Suppresses Growth and Induces Apoptosis in Prostate Carcinoma Cells in Culture and Nude Mouse Xenograft: PI3K-Akt Pathway as Potential Target
Constitutive activation of phosphoinositide 3-kinase (PI3K)-Akt pathway transmits growth regulatory signals which play a central role in promoting survival, proliferation and angiogenesis in human prostate cancer (PCa) cell. Here we assessed inositol hexaphosphate (IP6) efficacy against invasive hum...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2009
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2819750/ https://ncbi.nlm.nih.gov/pubmed/19920184 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-2805 |
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